Full Members

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Portrait photo of Parisa Ariya

Parisa Ariya

Department of Chemistry

The Parisa lab investigates how RNA and DNA bioaerosols affect ice microphysics, and use four-dimensional physicochemical tracking of air or water-borne virus.

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Mathieu Blanchette

Mathieu Blanchette

School of Computer Science

The Blanchette lab develops cutting-edge bioinformatics and machine learning approaches to study RNA structure and regulation.

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Guojun Chen

Guojun Chen

Department of Biomedical Engineering

The Chen lab focuses on developing intelligent delivery systems for various types of drugs, including RNAs, with an ultimate goal to achieve precision medicine.

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Masad J Damha

Masad J Damha

Department of Chemistry

The Damha lab conducts research at the interface of organic synthesis and chemical biology, studying the effects of chemical modification on the biological activity and structure of DNA and RNA.

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Josée Dostie

Josée Dostie

Department of Biochemistry

The Dostie lab is working towards defining how long non-coding RNAs control gene expression and chromatin in the nucleus and cytoplasm of mammalian cells.

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Thomas Duchaine

Thomas Duchaine

Department of Biochemistry

The Duchaine lab's research program revolves around the the RNA- interference (RNAi) pathways, such as microRNA-mediated silencing, and their implications in cancer and development.

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Marc Fabian

Marc Fabian

Department of Oncology

The Fabian lab investigate how microRNAs, RNA binding proteins and ribonucleoprotein complexes translationally repress and/or destabilize target mRNAs in mammalian cells.

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William Foulkes

William Foulkes

Department of Human Genetics

The Foulkes lab's interests lie in how defects in microRNA biogenesis affect human health. His studies of the DICER1 endoribonuclease have elucidated the clinicopathological basis of DICER1 syndrome.

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Anne Gatignol

Anne Gatignol

Department of Medicine

The Gatignol lab studies the interactions between HIV and the components of the RNA interference machinery. They also develop RNA-based technologies to target HIV and its cellular cofactors and inhibit viral replication.

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Kalle Gehring

Kalle Gehring

Department of Biochemistry

The Kalle Gehring lab investigates the structural biology of RNA, RNA-protein interactions and the translation initiation apparatus.

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Philippe Gros

Philippe Gros

Department of Biochemistry

The Gros lab uses genomics and transcriptomics to study the impact of mutations on leukocytes numbers and function in the context of susceptibility to infectious and inflammatory diseases in humans and mice.

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Corinne Hoesli

Corinne Hoesli

Department of Chemical Engineering

The Hoesli lab biomanufactures cell therapy products via process optimization, bioreactor design and novel encapsulation systems.

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Sidong Huang
  • Sidong Huang

Department of Biochemistry

The Huang lab identifies cancer therapeutic strategies using RNA-guided functional screening technologies based on RNAi and CRISPR.

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Amine Kamen

Amine Kamen

Department of Bioengineering

The Kamen lab examines how the viral vaccine production process can be accelerated by understanding how cells and viruses interact, as well as the cellular metabolic state needed for maximum productivity.

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Larry Lands

Larry Lands

Department of Pediatrics

The Larry Lands translational research lab advances innovation in inhaled RNA therapeutics for lung diseases.

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David Langlais

David Langlais

Department of Human Genetics

The Langlais lab investigates the epigenetic regulatory mechanisms of RNA expression in the context of normal and pathological inflammation.

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Chen Liang

Chen Liang

Department of Medicine

The Liang lab investigates the replication and pathogenesis of RNA viruses including HIV-1 and SARS-CoV-2, as well as host innate immune responses and antiviral drug discovery.

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Rongtuan Lin

Rongtuan Lin

Department of Microbiology and Immunology

The Lin lab investigates the positive and negative regulation of antiviral response and develops novel strategies to control virus infection.

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Nathan Luedtke

Nathan Luedtke

Department of Chemistry

The Luedtke lab uses chemical synthesis and biological evaluation of modified nucleosides and nucleotides, to develop new tools for probing DNA chemistry and biology and generate new leads for anti-viral and anti-cancer agents.

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Maureen McKeague

Maureen McKeague

Departments of Chemistry & Pharmacology

The McKeague lab studies and targets the chemistry of genomes for the development of RNA cancer therapeutics and biosensing applications.

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Anthony Mittermaier

Anthony Mittermaier

Department of Chemistry

The Mittermaier lab develops new biophysical tools in order to better understand how biological macromolecules function at the atomic level.

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Nicolas Moitessier

Nicolas Moitessier

Department of Chemistry

The Moitessier lab's approach is to integrate advanced organic synthesis, computational chemistry, and biological testing to significantly improve the molecular discovery rate.

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Andrew Mouland

Andrew Mouland

Department of Medicine
Division of Experimental Medicine

The Mouland lab focuses on the molecular and cellular biology of pandemic and emerging RNA viruses, and studies RNA-protein condensates and key virus-host interactions.

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Bhushan Nagar

Bhushan Nagar

Department of Biochemistry

The Nagar lab uses structural biology approaches to uncover the basis for the RNA-protein interactions underlying human anti-viral defences.

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Hamed Najafabadi

Hamed Najafabadi

Department of Human Genetics

The Najafabadi lab combines machine learning and statistical inference with genomics datasets to characterize the regulatory networks linking transcription factors, RNA-binding proteins, and non-coding RNAs with cell identity and human diseases.

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Joaquin Ortega

Joaquin Ortega

Department of Anatomy and Cell Biology

The Ortega lab uses cryo-electron microscopy and biophysical methods to study the ribosome assembly process in bacteria, which can lead to development of new antibiotics.

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Jerry Pelletier

Jerry Pelletier

Department of Biochemistry

The Pelletier lab has identified and is characterizing, through chemical biology and genetic approaches, small molecule inhibitors of translation that function as molecular staples – locking RNA binding proteins to RNA to inhibit gene expression.

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Stephane Richard

Stephane Richard

Department of Oncology
Department of Medicine

The Richard lab focuses on how small molecule inhibitors of arginine methylation influences RNA processes, such as mRNA splicing, dsRNA generation for innate immune stimulation, mRNA processing, degradation and translation.

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Selena Sagan

Selena Sagan

Department of Microbiology and Immunology

The Sagan lab aims to improve our understanding of how positive-sense RNA viruses usurp the host cell, replicate their genomes, and cause disease. They hope to gain insight into RNA regulation and identify novel avenues for antiviral intervention.

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Reza Salavati

Reza Salavati

Institute of Parasitology

The Salavati lab uses a multidisciplinary approach to annotate and target the essential common pathways in parasitic pathogens, including RNA editing.

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Hanadi Sleiman

Hanadi Sleiman

Department of Chemistry

The Sleiman lab aims to take DNA out of its biological context, and to use this molecule to build two- and three-dimensional structures.

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Nahum Sonenberg

Nahum Sonenberg

Department of Biochemistry

The Sonenberg lab's research focuses on the molecular basis of the control of protein synthesis in eukaryotic cells and its importance in cancer and neurological diseases.

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Maria Vera Ugalde

Maria Vera Ugalde

Department of Biochemistry

The Vera lab investigates the molecular mechanisms that enable cells to survive environmental and age-related stresses using cutting-edge single molecule fluorescence microscopy techniques.

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Silvia Vidal

Silvia Vidal

Department of Human Genetics

The Vidal lab studies host-pathogen interactions using mouse models of infection and functional genomic approaches, with a main focus on RNA viruses with pandemic potential.

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Jérôme Waldispühl

Jérôme Waldispühl

School of Computer Science

The Waldispühl lab conducts research in computational molecular biology with a particular interest on RNA structural bioinformatics and cheminformatics.

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Stephanie C Weber

Stephanie C Weber

Departments of Biology and Physics

The Weber lab studies how phase-separated condensates regulate transcriptional activity, and how nascent RNA, in turn, impacts condensate size and stability.

Associate Members

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Imed Gallouzi

Imed Gallouzi

Professor of Bioscience, BESE
Associate Director
Chief Operation Officer (COO)
KAUST Smart-Health Initiative (KSHI)
King Abdullah University of Sciences and Technology (KAUST)

Professor Emeritus, Biochemistry Department, Goodman Cancer Institute, Ã山ǿ¼é

The Gallouzi lab focuses on RNA Binding Protein mediated regulation of mRNA metabolism in health and disease.

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Eric Lecuyer

Eric Lecuyer

Full Professor, Montreal Clinical Research Institute (IRCM)

Full Professor, Department of Biochemistry and Molecular Medicine, University of Montreal

Adjunct Professor, Department of Medicine, Division of Experimental Medicine, Ã山ǿ¼é

The Lecuyer lab studies how RNA molecules and regulatory machineries are deployed in subcellular space, how this impacts various cellular functions, and how defects in localized RNA regulation contribute to disease etiology.

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Marlene Oeffinger

Marlene Oeffinger

Associate Research Professor, Montreal Clinical Research Institute (IRCM)
Professor, Biochemistry & Molecular Medicine department, University of Montreal

Adjunct Professor, Department of Medicine, Division of Experimental Medicine, Ã山ǿ¼é

The Oeffinger lab studies the architecture, functional niches, and nucleocytoplasmic transport of RNA Ribonucleoprotein assemblies to better understand the regulation of these pathways and how defects in RNP regulation are linked to DNA damage and repair, and the etiology of neurodegenerative diseases such as ALS.

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Martin Sauvageau

Martin Sauvageau

Assistant Research Professor, Montreal Clinical Research Institute (IRCM)

Assistant Professor, Biochemistry & Molecular Medicine department, University of Montreal

Adjunct Professor, Biochemistry department, Ã山ǿ¼é

The Sauvageau lab aim to better understand the impact that long noncoding RNAs have on development and diseases and use RNA-based mechanisms to design novel diagnostics and therapies.