Larry C. Lands
Professor听
MD, PhD听
- MDCM, 缅北强奸, 1981听
- Pediatrics, Montreal Children鈥檚 Hospital, 1984听
- Pediatric Respiratory Medicine, Montreal Children鈥檚 Hospital, 1986听
- PhD, Medical Sciences, McMaster University, 1993
Dr. Larry Lands鈥 clinical research focuses on improving the functional capacity of those living with chronic conditions such as Cystic Fibrosis (CF) and obesity.听
Our goal is to improve the functional ability of those living with conditions that impair their breathing capacity. We are developing oscillometry as a simple non-invasive test to assess lung function across the lifespan. We are studying why some adolescents living with obesity have exercise limitation so that we can improve their level of fitness. Our laboratory-based research is focused on improving the function of the epithelial cells lining the airways in chronic lung disease including Cystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD), asthma, and Chronic Obstructive Pulmonary Disease. We are developing novel inhaled lipid nanoparticles to deliver antisense oligonucleotide and mRNA constructs to correct the genetic mutations that cause CF and PCD, reduce inflammation in asthma, and rejuvenate the respiratory epithelium in Chronic Obstructive Pulmonary Disease. As a member of the Department of Pediatrics, Dr. Lands shared that he gains from 鈥the multidisciplinary and interdisciplinary clinical and scientific capacities across the Department鈥.
- Respiratory physiology听
- Exercise physiology听
- Lipid nanoparticles听
- Respiratory epithelial cellular molecular biology听
- Oscillometry across the lifespan听
- Exercise capacity in chronic conditions听
- Inhaled RNA therapeutics听听
- Cystic Fibrosis听
- Primary Ciliary Dyskinesia听
- Chronic Obstructive Pulmonary Disease听
- Obesity听
- Mucolytic therapies听
- Chair of the Research Committee of the Canadian Thoracic Society听听
- Chair of Cystic Fibrosis Canada鈥檚 Research Advisory Council听