The Neuro - Profile: Peter McPherson

An open solution to improving research reproducibility

�山ǿ�� — Wed, 18 Dec 2024 16:12:19 +0000

Academic and industry scientists collaborate on a new method to characterize research antibodies

Open Science project funded for $1.5M

�山ǿ�� — Tue, 12 Nov 2024 16:51:24 +0000

YCharOS antibody characterization platform addresses the “reproducibility crisis” in research

An innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.

YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.

Recreating a hallmark of Parkinson's disease in human neurons

�山ǿ�� — Tue, 08 Oct 2024 14:47:43 +0000

Scientists use stem cells to follow development of protein bodies characteristic of neurological disease

Open Science antibody characterization project receives $4-million grant

�山ǿ�� — Mon, 14 Mar 2022 19:56:23 +0000

YCharOS is an independent quality assessment initiative to improve research results

An antibody characterization project with partners at The Neuro will be able to expand thanks to funding from Génome Québec.

YCharOS forms key industry advisory committee and releases first open data

�山ǿ�� — Tue, 22 Jun 2021 13:11:31 +0000

Leading antibody reagent and knockout cell line manufacturers team up to address life science reproducibility crisis

YCharOS Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins, is pleased to announce the publication of its first characterization data and formation of its Industry Advisory Committee (IAC).

Improving research with more effective antibodies

�山ǿ�� — Tue, 15 Oct 2019 16:03:40 +0000

Scientists demonstrate flaws in protein detection tools, and outline a solution

A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.

Antibodies are used in laboratories and clinics to study proteins, which are the biomolecules that translate information from an organism’s genes into the structure, function, and regulation of its tissues and organs. Genetic mutations can cause protein imbalances or malfunctions, leading to human disease.

June is ALS Month

�山ǿ�� — Thu, 07 Jun 2018 14:55:40 +0000

A look at the latest ALS research and clinical care at The Neuro

Amyotrophic lateral sclerosis (ALS) is a terrible disease with no known cure. Research at The Montreal Neurological Institute and Hospital (The Neuro) is uncovering data that could help find effective treatments for ALS.

The Neuro and Thermo Fisher Scientific Partner to Fight Neurodegenerative Disease

�山ǿ�� — Mon, 05 Mar 2018 15:12:01 +0000

Industry and academia to share expertise in effort to develop improved methods to produce and characterize antibodies and reagents for neurological research

ALS – Fostering awareness of a devastating disease

�山ǿ�� — Fri, 02 Jun 2017 14:59:25 +0000

ALS takes away the patient’s motor functions one at a time, and the progress of finding effective drugs to counter its insidious effects has been slow. June is ALS Month, a good time to update the public on the latest developments in ALS research taking place at The Neuro.

The Montreal Neurological Institute and Hospital (The Neuro) is recognized as a leading Canadian centre for research into amyotrophic lateral sclerosis (ALS) as well as for its care of ALS patients.

Epileptic encephalopathy linked to protein trafficking gene

�山ǿ�� — Fri, 18 Nov 2016 16:49:28 +0000

Researchers have linked a debilitating neurological disease in children to mutations in a gene that regulates neuronal development through control of protein movement within neuronal cells.

MNI researchers receive funding to study ARSACS

�山ǿ�� — Thu, 24 Nov 2016 16:53:42 +0000

Two researchers at the Montreal Neurological Institute and Hospital (MNI) of �山ǿ�� have received funding to study a devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk.

Major ALS Research Funding Announced

�山ǿ�� — Tue, 22 Nov 2016 19:50:02 +0000

MNI scientists will study stem cells, genetic mutations to develop new treatments

Researchers at the Montreal Neurological Institute of �山ǿ�� who are playing key roles in uncovering the mechanisms underlying ALS will share in $3.9 million in research funding, part of $4.5 million announced on Nov. 23 by the ALS Society of Canada in partnership with Brain Canada.

ALS Awareness Month – June 2016

�山ǿ�� — Fri, 10 Jun 2016 20:45:35 +0000

The Neuro is recognized as a major Canadian center for ALS research and patient care. During June, designated ALS Month, The Neuro redoubles its efforts to inform the public and the media about amyotrophic lateral sclerosis (ALS), and urges all to help support ALS research.

Scientists and Clinicians at The Montreal Neurological Institute and Hospital receive funding for ALS research

�山ǿ�� — Fri, 20 Nov 2015 15:46:55 +0000

The ALS Ice Bucket Challenge One Year Later

On November 19 2015, marking the anniversary of the announcement of the 2014 ALS Ice Bucket Challenge results and partnership between ALS Canada and Brain Canada, ALS Canada was at The Montreal Neurological Institute and Hospital – The Neuro, to announce the final recipients of their 2015 grant competition. Four researchers and clinicians at The Neuro were among those recipients for their groundbreaking work in the ALS research field.

ALS Awareness Month – June

�山ǿ�� — Tue, 02 Jun 2015 14:36:53 +0000

As a major Canadian centre for amyotrophic lateral sclerosis (ALS) research and treatment, the Montreal Neurological Institute and Hospital - The Neuro, invites the public and the media to learn more about the disease and current research and treatments, to donate money for ALS research and to wear the national emblem of ALS in Canada, the blue cornflower, during ALS Awareness Month in June.

Using patients’ own cells to accelerate research into neurological disease

�山ǿ�� — Tue, 31 Mar 2015 13:29:50 +0000

$1 M gift from Mr. J. Sebastian van Berkom launches translational research into neurological disease

A patient’s very own skin cells may hold the key to new treatments and even cures for devastating neurological diseases. A generous $1 million donation from Mr. J. Sebastian van Berkom, and critical partnerships with Brain Canada, Laval University, Marigold Foundation and the FRQS-Réseau Parkinson Quebec are driving an innovative, iPSC (induced pluripotent stem cell) research platform that will transform research into Parkinson’s and other neurological diseases.

Breakthrough in understanding how cancer cells metastasize

�山ǿ�� — Thu, 26 Feb 2015 15:25:10 +0000

Montreal Neurological Institute scientists discover a new mechanism driving spread of cancer

A protein commonly found in human cells could be an important switch that activates cancer cell metastasis, according to a new study by researchers at the Montreal Neurological Institute and Hospital - The Neuro at �山ǿ�� and the MUHC. The finding focuses attention on a biological mechanism that until now was largely overlooked. The discovery of the protein’s effect significantly expands our understanding of epithelial cancers such as breast and lung cancer.