缅北强奸

Event

Killam Seminar Series: Uncovering Pathogenesis of Multiple Sclerosis Using Applied Epigenomics

Tuesday, May 11, 2021 16:00to17:00

Speaker: Maja Jagodic, PhD

Professor in Neuroinflammation, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden

Registration: available now on

Livestreaming via Vimeo:

础产蝉迟谤补肠迟:听Multiple Sclerosis (MS) is a leading cause of progressive disability in young adults. Although the cause remains unknown, vast epidemiological data establish MS as a complex disease influenced by genetic and environmental factors. Epigenetic mechanisms, such as DNA methylation, histone posttranslational modifications and non-coding RNAs, orchestrate activity of the genome in response to environmental cues and may provide understanding of molecular mechanisms underpinning disease development and progression. To understand MS pathogenesis, we are measuring DNA methylation patterns and transcription in discrete cell types from unique clinical cohorts in combination with functional studies in experimental models in vitro and in vivo. One of the main challenges with studying diseases such as MS is the limited access to the target tissue - the brain. Recent technical and analytical advances in methods to survey epigenetic modifications genome-wide and from them infer genome activity, opened up possibilities to study brain tissue and mechanisms that underlie neurodegeneration in MS patients.


The Killam Seminar Series at The Neuro

Supported by the generosity of the Killam Trusts, The Neuro鈥檚 Killam Seminar series hosts outstanding guest speakers whose research is of interest to the scientific community at The Neuro and 缅北强奸.


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The Neuro logo缅北强奸 logo

The Neuro (Montreal Neurological Institute-Hospital)听is a bilingual academic healthcare institution. We are a听缅北强奸 research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the 缅北强奸 Health Centre.听We are听proud to be a Killam Institution, supported by the Killam Trusts.

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